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Polypharmacy in oligopopulations: what psychiatric genetics can teach biological psychiatry
1Laboratory of Neurophenomics, Institute of Psychiatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA. anicules@iupui.edu
Abstract:
Psychiatric genetics and genomics have made major strides in recent years. Some of that knowledge has yet to permeate in the clinical practice of biological psychiatry. The example of cancer-genetics, biology and clinical treatments may be profitable in terms of accelerating translational integration in psychiatry. We propose that current developments in genetics and genomics point to an Early Low-Dose Rational Polypharmacy in Oligopopulations model for psychiatric pharmacotherapy.
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