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Crohn's disease: innate immunodeficiency?

Jesus-K Yamamoto-Furusho1, Joshua-R Korzenik

  • 1Gastrointestinal Unit, Massachusetts General Hospital, 55 Fruit Street, Boston, Massachusetts 02114, USA. kazuofurusho@hotmail.com

World Journal of Gastroenterology
|November 16, 2006
PubMed
Summary

Crohn's disease may stem from innate immune dysfunction, not just T-cell issues. Stimulating the innate immune system, such as with granulocyte-macrophage colony-stimulating factor (GM-CSF), shows clinical benefit in Crohn's disease patients.

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