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Published on: April 19, 2019
Comparison of the impact of cardiovascular guidelines on a working population
Pierre Gillois1, Frédérique Claudot, Gilles Chatellier
1Laboratoire SPIEAO, Faculté de Médecine Nancy I, France.
Insights
Clinical Practice Guidelines (CPGs) for hypertension management showed poor agreement and did not consistently identify high-risk patients. Risk calculation, not limited variables, should guide healthcare screening for better accuracy.
Area of Science:
- Cardiology
- Public Health
- Health Policy
Background:
- Clinical Practice Guidelines (CPGs) are increasingly vital in medicine, standardizing knowledge for patient care.
- Hypertension and dyslipidemia management guidelines significantly influence healthcare decisions.
Purpose of the Study:
- To evaluate the impact of different Clinical Practice Guidelines (CPGs) on a working population.
- To compare CPG classifications against the Framingham cardiovascular risk calculation as a gold standard.
Main Methods:
- Analysis of two hypertension management CPGs (1997, 2000) and one dyslipidemia CPG.
- Comparison of CPG-based patient classification with Framingham risk scores in a sample of 2817 French patients.
Main Results:
- Hypertension CPGs screened over a quarter of the working population.
- Patients on drug treatment exhibited higher mean cardiovascular risk than those not treated or not screened by CPGs.
- Some high-risk patients were missed by CPGs due to insufficient or inadequate variables.
Conclusions:
- Significant discrepancies exist between different versions of hypertension CPGs.
- Healthcare screening should prioritize comprehensive risk calculation over limited variables.
- Feedback to CPG developers can improve guideline consistency and reduce recommendation variability.
Unlabelled:
The influence of guidelines is more and more important in the medicine using standardised knowledge as Clinical Practice Guideline (CPG).
Objectives:
1) Determine the impact of different CPGs on a working population 2) Using the Framingham risk calculation as gold standard to check the CPG classifications.
Methods:
This work is done in the context of two hypertension management CPGs published in 1997 and 2000, and one dyslipidemia CPG by the French agency HAS. A French regional study sample of 2817 patients was selected. The results of the classification system by CPG were compared to those given by the chosen gold standard: Framingham cardiovascular risk calculation.
Results:
The HBP CPG concerns more of the quarter of the working population. The mean of the cardiovascular risk calculation for the patients with drug treatment is higher than for the patients with no drug treatment and for those not screened by the CPG. Some patients with a very high calculated risk, are not selected by the screening CPG based on too few or on not adequate variables.
Conclusions:
For the two High Blood Pressure Management CPGs, the selected patients are not distributed the same way in the two CPGs. Observed agreement is poor between the two hypertension CPG versions. Screening people for specific health care should be based on risk calculation not on few variables. Feeding back our results to the CPG creator group should reduce the variability of recommendations.
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