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Updated: Jul 18, 2026
Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo
Published on: February 2, 2016
Expression of the forkhead transcription factor FoxN4 in progenitor cells in the developing Xenopus laevis retina and
Lisa E Kelly1, Srivamsi Nekkalapudi, Heithem M El-Hodiri
1Center for Molecular and Human Genetics, Columbus Children's Research Institute, Columbus, OH 43205, USA.
Abstract:
Forkhead proteins are involved in gene regulation in a large variety of developmental situations. Several forkhead gene products are expressed in the developing eye and brain. Here we characterize the expression of FoxN4 during Xenopus development. We report that FoxN4 is expressed in the eye from the earliest stages of specification through retinal maturation. FoxN4 is also expressed in the pallium, optic tectum, isthmus, reticular formation, and in cells lining the ventricle of the tadpole brain.
