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Updated: Jul 18, 2026

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A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Effects of mandibular symphyseal distraction osteogenesis on mandibular structures
Siddik Malkoç1, Haluk Işeri, Ali Ihya Karaman
1Department of Orthodontics, School of Dentistry, University of Selçuk, Konya, Turkey. siddikmalkoc@yahoo.com
Summary
Mandibular symphyseal distraction osteogenesis effectively widens the dental arch and skeletal structures, offering a stable, non-extraction solution for dental crowding. This method increases arch width without significant changes to bigonial or ramal angles.
Area of Science:
- Orthodontics
- Oral and Maxillofacial Surgery
- Dental Research
Background:
- Mandibular hypoplasia and dental crowding are common orthodontic concerns.
- Traditional treatments may involve extractions or complex surgical procedures.
Purpose of the Study:
- To evaluate the effects of mandibular symphyseal distraction osteogenesis (MSDO) on dental and skeletal structures.
- To assess the efficacy of a tooth- and bone-borne distraction device.
Main Methods:
- A sample of 20 patients (ages 15.8-23.3 years) underwent MSDO.
- Distraction was activated at 1 mm/day and maintained for approximately 90 days.
- Data collected via posteroanterior cephalograms and study casts at baseline, end of distraction, and long-term follow-up (24.1 months).
Main Results:
- Significant increases in bimolar width and decreases in bicondylar width were observed.
- Maximum arch widening occurred between mandibular canines, decreasing towards the molars.
- No significant changes in bigonial width or ramal angles were noted.
Conclusions:
- MSDO is an effective non-extraction treatment for mandibular dental crowding.
- The procedure successfully increases mandibular skeletal and dental arch widths.
- Treatment results demonstrated long-term stability.

