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A Method to Study the C924T Polymorphism of the Thromboxane A2 Receptor Gene
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Published on: April 1, 2019

A coding VKORC1 Asp36Tyr polymorphism predisposes to warfarin resistance.

Ronen Loebstein1, Ilana Dvoskin, Hillel Halkin

  • 1Institute of Clinical Pharmacology and Toxicology, Sheba Medical Center, Tel Hashomer, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, Israel.

Blood
|November 18, 2006
PubMed
Summary

A newly identified VKORC1 Asp36Tyr genetic variant is a significant marker for high warfarin dose requirements. This finding helps characterize genetic factors influencing warfarin resistance and optimize dosing strategies.

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