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Related Experiment Videos

Radiation recall dermatitis with cefotetan: a case study.

Ayodele Ayoola1, Young Joo Lee

  • 1Department of Medicine, Franklin Square Hospital Center, Baltimore, Maryland 21237, USA. ayodeleayoola@hotmail.com

The Oncologist
|November 18, 2006
PubMed
Summary

Radiation recall dermatitis (RRD) is a skin reaction in previously irradiated areas after medication. This case highlights a potential new association between RRD and the antibiotic cefotetan.

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Area of Science:

  • Oncology
  • Dermatology
  • Pharmacology

Background:

  • Radiation recall dermatitis (RRD) is a skin reaction occurring in a previously irradiated area after drug administration.
  • This phenomenon can manifest days to years after radiation exposure.

Observation:

  • A 54-year-old woman with a history of lung cancer treated with radiation and chemotherapy developed acute cholecystitis.
  • She was administered cefotetan and subsequently developed a tender, erythematous rash in her previously irradiated thoracic region.

Findings:

  • The patient's rash resolved after cefotetan was discontinued, suggesting a drug-induced reaction.
  • This case represents a potential new association between radiation recall dermatitis and cefotetan.

Implications:

Related Experiment Videos

  • Clinicians should consider RRD in patients presenting with rashes in irradiated areas, especially after new medication initiation.
  • This case expands the known spectrum of drugs associated with radiation recall dermatitis.