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Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington's Disease
Published on: June 9, 2018
A multiparametric brain and cord MR imaging study of a patient with Hirayama disease
A Gallo1, M A Rocca, P Tortorella
1Neuroimaging Research Unit, Department. of Neurology, Scientific Institute and University Ospedale San Raffaele, Milan, Italy.
Abstract:
In this study, we used a multiparametric MR imaging approach to assess a patient with Hirayama disease (HD). We found that cervical cord damage extends beyond cord T2-visible lesions. We also showed an altered pattern of cortical activations during movements of clinically unaffected limbs. Whereas this study suggests a more widespread cord involvement in HD than seen on routine MR imaging, its cause remains unclear (vascular damage versus a primary lower motor neuron disease).
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