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Left main coronary thrombosis with essential thrombocythemia
Zekeriya Nurkalem1, Nevzat Uslu, Sevket Gorgulu
1Cardiology Department, Siyami Ersek Thoracic and Cardiovascular Surgery Center, Istanbul, Turkey. zeknurkalem@yahoo.com
Journal of Thrombosis and Thrombolysis
|November 18, 2006
Summary
Essential thrombocythemia, a condition causing high platelet counts, significantly increases thrombosis risk. This case highlights successful surgical management of left main coronary thrombosis in an essential thrombocythemia patient.
Area of Science:
- Cardiology
- Hematology
Background:
- Essential thrombocythemia is a myeloproliferative neoplasm characterized by elevated platelet counts.
- This condition is associated with a significantly increased risk of arterial and venous thrombosis.
Observation:
- A 71-year-old woman presented with stable angina, subsequently diagnosed with left main coronary thrombosis via angiogram.
- The patient had a recent diagnosis of essential thrombocythemia made one week prior to the angiogram.
Findings:
- Initial medical treatment and excimer laser therapy failed to resolve the left main coronary thrombus.
- Thrombopheresis was performed to reduce platelet count before coronary surgery.
- Successful coronary artery bypass grafting resulted in complete patient recovery.
Implications:
- This case underscores the critical link between essential thrombocythemia and coronary thrombosis.
- It demonstrates the efficacy of surgical intervention combined with platelet reduction strategies in managing complex coronary thrombosis.
- Highlights the importance of considering thrombotic risk in patients with essential thrombocythemia.
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