Bilateral processing in chemical synapses with electrical 'ephaptic' feedback: a theoretical model

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Real-time Electrophysiology: Using Closed-loop Protocols to Probe Neuronal Dynamics and Beyond
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Leonid P Savtchenko1

  • 1Dnepropetrovsk National University and International Center of Molecular Physiology, Dnepropetrovsk Division, Dnepropetrovsk, per. Nauchniy, 15, 49050 Dnepropetrovsk, Ukraine. leon@ff.dsu.dp.ua

Mathematical Biosciences
|November 23, 2006
PubMed

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Chemical Synapses

Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
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Neurons communicate with one another by passing on their electrical signals to other neurons. A synapse is the location where two neurons meet to exchange signals. At the synapse, the neuron that sends the signal is called the presynaptic cell, while the neuron that receives the message is called the postsynaptic cell. Note that most neurons can be both presynaptic and postsynaptic, as they both transmit and receive information.
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Electrical Synapses

Electrical synapses found in all nervous systems play important and unique roles. In these synapses, the presynaptic and postsynaptic membranes are very close together (3.5 nm) and are actually physically connected by channel proteins forming gap junctions.
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