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Updated: Jul 18, 2026

Methods for Detecting Cough and Airway Inflammation in Mice
Published on: August 2, 2024
Clinical assessment of chronic cough severity
Anita A Raj1, Surinder S Birring
1Department of Respiratory Medicine, King's College Hospital, London SE5 9RS, UK.
Abstract:
The assessment of cough severity solely through consultation with the patient is limited by its subjective nature and variability of physician judgement. The assessment of cough has been hampered by a paucity of objective tools, those available have been poorly validated, non-standardized and are impractical for clinical use. Recent developments have overcome some of these problems and a variety of tools can now be used to assess cough that include visual analogue scales (VAS), quality-of-life questionnaires, cough reflex sensitivity measurement and automated cough frequency monitors. These tools can be used to validate the presence of cough and assess response to therapy. They will also have an important role in clinical trials.
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