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Updated: Jul 18, 2026
Visualization of Chondrocyte Intercalation and Directional Proliferation via Zebrabow Clonal Cell Analysis in the Embryonic Meckel’s Cartilage
Published on: October 21, 2015
Chondroblastoma of the apex portion of petrousal bone
Grégory Dran1, Eric Niesar, Fanny Vandenbos
1Department of Neurosurgery, Gui de Chauliac Hospital, 2 av Emile Bertin Sans, 34000, Montpellier, France. g-dran@chu-montpellier.fr
Background:
Skull chondroblastoma is extremely rare. We described in this study the first case of petrousal bone apex chondroblastoma.
Methods:
The tumor occurred in a 12-year-old girl and was revealed by left hypoacusis, vertigo, and walking instability. Computerized tomography scan depicted well-demarcated and osteolytic lesion of the left petrousal bone just before the internal acoustic meatus. The tumor was operated on by a subtemporal approach with a subtotal resection. Lesion recurred and was operated a second time by a combined approach subtemporal and translabyrinthine. This treatment was completed by radiotherapy. We used a combination of photon therapy and proton therapy. Outcome was good and free of recurrence 36 months after the second operation.
Conclusion:
Proton therapy can be particularly useful for skull base tumors frequently radioresistant and near very important structures. This case is the first one of a successful treatment by proton therapy for chondroblastoma recurrence.
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