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Headache attributed to infection: observations on the IHS classification (ICHD-II)
E Marchioni1, E Tavazzi, G Bono
1Institute of Neurology, IRCCS C. Mondino, Pavia, Italy. enrico.marchioni@mondino.it
Abstract:
The aim of this study was to revise some topics in the chapter "Headache attributed to infections" in the last International Headache Society (IHS) classification. The authors searched for original studies and reviews about headache associated with infections. A checklist was submitted to 15 neurologists to quantify the relevance, comprehensibility and coherence between definitions, criteria and comments for each paragraph. The following paragraphs were fully discussed: (1) headache attributed to lymphocytic meningitis. This topic, being rather heterogeneous, should be divided into different subgroups; (2) headache attributed to HIV/AIDS. Distinctive features are not specified and diagnostic criteria are rather confusing; and (3) chronic post-infection headache. Diagnostic criteria should be reconsidered as the symptom "pain" is not the main diagnostic criterion. The authors propose the revision of three paragraphs of the new IHS classification to better define the most likely headache profile in specific CNS infections. The authors also underline the need to plan further ad hoc prospective studies.
Insights
This study revises the International Headache Society classification for headaches linked to infections. Proposed changes aim to clarify diagnostic criteria for meningitis, HIV/AIDS, and chronic post-infection headaches.
Area of Science:
- Neurology
- Infectious Diseases
Background:
- The International Headache Society (IHS) classification requires updates regarding headaches associated with infections.
- Existing diagnostic criteria for certain infection-related headaches are unclear or confusing.
Purpose of the Study:
- To revise specific sections of the IHS classification concerning headaches attributed to infections.
- To improve the clarity and accuracy of diagnostic criteria for infection-related headaches.
Main Methods:
- Literature search for original studies and reviews on headache and infections.
- Expert review by 15 neurologists using a checklist to assess relevance, comprehensibility, and coherence.
- Focused discussion on headaches attributed to lymphocytic meningitis, HIV/AIDS, and chronic post-infection conditions.
Main Results:
- Headache attributed to lymphocytic meningitis is heterogeneous and needs subgrouping.
- Diagnostic criteria for headache attributed to HIV/AIDS lack specificity and are confusing.
- Diagnostic criteria for chronic post-infection headache require reconsideration, as pain is not the sole defining feature.
Conclusions:
- Proposed revisions to the IHS classification will enhance the definition of headache profiles in specific CNS infections.
- Further prospective studies are recommended to refine understanding and classification of infection-related headaches.
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