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Updated: Jul 18, 2026

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
Fibrous lipoblastoma with 8q11.2 abnormality
Randall D Craver1, Stephen Henrich, Yuan S Kao
1Department of Pathology, Louisiana State University Health Science Center, New Orleans, LA 70112, USA. rcrave@lsuhsc.edu
Abstract:
A 3-month-old African American female infant had a rapidly growing lipoblastoma with a prominent fibrous component in the soft tissue of the left lateral knee, which recurred at 10 months. Cytogenetic analysis revealed deletion of 8(q11.2q13) with a 19(q12q13.3) insertion at that site, confirming that this is closely related to the conventional lipoblastoma. The presence of multivacuolated lipoblasts and the staining characteristics (no staining for CD99, CD34, or smooth muscle actin) distinguish this from the recently described lipofibromatosis.
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