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Primary appendiceal malignancy: a clinicopathologic study
Hwa-Tzong Chen1, Yeu-Tsu M Lee, Andy Shaw-Bin Chou
1Department of Surgery, Buddhist Tzu Chi University, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
The Kaohsiung Journal of Medical Sciences
|November 23, 2006
Summary
Primary appendiceal cancer is rare. Adenocarcinoid tumors show better prognosis than adenocarcinomas, and palliative surgery can lead to long-term survival for disseminated appendiceal cancer.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Pathology
Background:
- Primary appendiceal cancer is an uncommon malignancy.
- Accurate preoperative diagnosis is challenging, often mistaken for acute appendicitis.
Purpose of the Study:
- To analyze clinicopathologic characteristics and outcomes of primary appendiceal cancer.
- To identify prognostic factors for appendiceal neoplasms.
Main Methods:
- Retrospective review of medical records for patients with appendiceal cancer over 10 years.
- Histopathological analysis of tumor subtypes: mucinous adenocarcinoma, colonic type adenocarcinoma, and adenocarcinoid.
Main Results:
- Eight patients (7 male, 1 female; median age 66) were identified.
- Adenocarcinoid tumors demonstrated a better prognosis compared to adenocarcinomas.
- Histologic subtype and extent of disease were significant prognostic indicators.
Conclusions:
- Appendiceal cancer diagnosis often occurs post-operatively.
- Adenocarcinoid histology is associated with a more favorable outcome.
- Palliative resection and chemotherapy can achieve long-term survival in advanced cases.
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