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Updated: Jul 18, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Increased isolation of methicillin-resistant Staphylococcus aureus in pediatric head and neck abscesses
Kathryn Ossowski1, Robert H Chun, Dana Suskind
1Section of Otolaryngology-Head and Neck Surgery, Pritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA.
Objective:
To compare the proportion of community-associated, methicillin-resistant Staphylococcus aureus (MRSA) infections in pediatric head and neck abscesses between 2 study periods.
Design:
Retrospective case review.
Setting:
Tertiary care pediatric otolaryngology practice. Patients Pediatric patients with head and neck abscesses presenting over 2 separate 2.5-year intervals: July 1999 through December 2001 and January 2002 through June 2004.
Interventions:
Incision and drainage of abscess.
Main Outcome Measures:
Type and antimicrobial susceptibility of cultured organisms.
Results:
We identified 21 abscesses in 19 patients from July 1999 through December 2001 and 32 abscesses in 32 patients from January 2002 through June 2004. Of the 21 abscesses in the first study period, 15 demonstrated pathogen growth compared with 29 of 32 abscesses in the second study period. In the first period, 6 (40%) of 15 abscesses yielded S aureus compared with 17 (58.6%) of 29 abscesses in the second period. The proportion of abscesses yielding MRSA increased from 0% (0/6) in the first study period to 64.7% (11/17) in the second study period (P<.01). All MRSA infections were considered to be community acquired.
Conclusions:
Our study demonstrates a statistically significant rise in the proportion of community-associated MRSA infections of the head and neck in the pediatric population at our institution. For communities where similar microbial recovery patterns exist, we suggest that a culture be obtained as soon as possible in a child presenting with a head and neck abscess to identify the organism. Until that time, the best empirical treatment is clindamycin, with other agents available if warranted by culture and sensitivity results. A treatment algorithm is presented.
Insights
Community-associated methicillin-resistant Staphylococcus aureus (MRSA) head and neck infections in children significantly increased between 2000 and 2004. Early cultures are recommended for pediatric head and neck abscesses to guide treatment.
Area of Science:
- Otolaryngology
- Pediatric Infectious Diseases
- Microbiology
Background:
- Head and neck abscesses are common in pediatric patients.
- The prevalence of community-associated methicillin-resistant Staphylococcus aureus (MRSA) has been increasing globally.
- Understanding the trends of MRSA in pediatric head and neck infections is crucial for effective management.
Purpose of the Study:
- To compare the incidence of community-associated MRSA in pediatric head and neck abscesses over two distinct time periods.
- To analyze the changes in microbial pathogens and their antimicrobial susceptibility in pediatric head and neck abscesses.
Main Methods:
- Retrospective case review of pediatric patients with head and neck abscesses.
- Involved two 2.5-year intervals: July 1999–December 2001 and January 2002–June 2004.
- Analysis of pathogen type and antimicrobial susceptibility from abscess cultures.
Main Results:
- The number of abscesses evaluated increased from 21 in the first period to 32 in the second.
- The proportion of abscesses yielding Staphylococcus aureus increased from 40% to 58.6%.
- A significant rise in MRSA was observed, from 0% in the first period to 64.7% in the second period (P<.01).
Conclusions:
- There was a statistically significant increase in community-associated MRSA head and neck infections in the pediatric population.
- Early culture and susceptibility testing are recommended for pediatric head and neck abscesses.
- Clindamycin is suggested as the initial empirical treatment, with adjustments based on culture results.
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