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Published on: July 20, 2022
Postoperative prophylactic peritoneal dialysis in neonates and infants after complex congenital cardiac surgery
Tijen Alkan1, Atf Akçevin, Halil Türkoglu
1V.K.V. American Hospital, Department of Cardiovascular Surgery, Istanbul, Turkey.
Insights
Peritoneal dialysis combined with perioperative ultrafiltration effectively managed fluid balance in infants undergoing complex heart surgery. This approach positively impacted survival rates in this vulnerable patient group.
Area of Science:
- Pediatric Cardiology
- Nephrology
- Critical Care Medicine
Background:
- Complex congenital heart disease (CCHD) surgery in infants often leads to fluid overload.
- Postoperative fluid management is critical for outcomes in neonates and infants undergoing cardiac repair.
Purpose of the Study:
- To evaluate the efficacy and outcomes of peritoneal dialysis (PD) in infants (0-1 year) following complex congenital cardiac surgery.
- To assess the impact of PD combined with perioperative ultrafiltration on fluid balance and survival.
Main Methods:
- Retrospective analysis of 756 infants (0-1 year) undergoing complex congenital cardiac surgery between May 1993 and December 2005.
- All patients received perioperative ultrafiltration; 186 (24.6%) required PD for fluid management.
- Indications, methods, duration of PD, and patient outcomes were analyzed.
Main Results:
- Peritoneal dialysis was required in 24.6% of cases, with transposition of great arteries being the most common diagnosis (133 cases).
- Prolonged PD was associated with low infant weight, pulmonary hypertensive crisis, and preoperative renal dysfunction (p < 0.05).
- No major PD catheter complications occurred; 12.3% developed acute renal failure, with a 2.15% mortality rate for all operated patients.
Conclusions:
- The combination of PD and perioperative ultrafiltration is effective for achieving negative fluid balance in infants with complex congenital heart disease.
- This integrated approach demonstrated a positive effect on survival in this high-risk pediatric population.
Abstract:
Peritoneal dialysis after complex congenital cardiac surgery was introduced to a group of neonates and infants (n = 756; age, 0 to 1 year) between May 1993 and December 2005. Indications of peritoneal dialysis were determined as well as methods, prolonged dialysis, and its outcomes. Demographic characteristics, preoperative risk factors, intraoperative variables, and postoperative complications were compared in 756 cases with ages below 1 year. All cases underwent ultrafiltration during the perioperative stage. One hundred eighty-six cases (24.6% of total) required peritoneal dialysis. The cardiac pathology was transposition of great arteries in 133 cases, tetralogy of Fallot in 37, aorticopulmonary window associated with interrupted aortic arch in 4 and total anomalous pulmonary venous return in 5, and other complex pathology in 7 cases. Prolonged peritoneal dialysis was usually required in infants with low weight, with episodes of pulmonary hypertensive crisis (p < 0.05), and with preoperative renal dysfunction. No major complication was observed related to the peritoneal dialysis catheter. Of 186 patients, 23 (12.3%) had acute renal failure, and 4 of them died (2.15% of all patients underwent operation, 17.3% of those with acute renal failure). It has been demonstrated that the combination of peritoneal dialysis with perioperative ultrafiltration application was effective in providing the required postoperative negative fluid balance in especially complex congenital heart cases and affected survival positively.
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