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[Local hyperthermia in benign prostatic hyperplasia].

K H Bichler1, W L Strohmaier, S H Flüchter

  • 1Abteilung für Urologie, Eberhard-Karls-Universität Tübingen.

Der Urologe. Ausg. A
|March 1, 1991
PubMed
Summary

Local microwave hyperthermia for benign prostatic hyperplasia (BPH) showed poor results. This treatment did not significantly improve voiding parameters or prostate size in most patients.

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Area of Science:

  • Urology
  • Oncology
  • Medical Physics

Context:

  • Benign prostatic hyperplasia (BPH) is a common condition in aging men.
  • Hyperthermia has emerged as a potential minimally invasive treatment for BPH.
  • Objective voiding parameters for BPH patients undergoing hyperthermia require further investigation.

Purpose:

  • To evaluate the efficacy of local microwave hyperthermia in treating BPH.
  • To assess changes in objective voiding parameters and prostate size after hyperthermia therapy.
  • To compare hyperthermia's effectiveness with established BPH treatments like transurethral resection (TUR).

Summary:

  • A phase II study treated 30 BPH patients with transrectal microwave hyperthermia (915 MHz) over eight sessions.
  • Post-treatment evaluation included transrectal ultrasound, urinary flow rate, and residual volume.
  • Only 2 out of 28 evaluable patients showed clinical improvement; voiding parameters and prostate size remained largely unchanged.

Impact:

  • Local microwave hyperthermia demonstrated a low success rate (7.1%) for BPH treatment.
  • The findings suggest hyperthermia is not currently an effective alternative to TUR for BPH.
  • Further research may be needed to optimize hyperthermia protocols or identify specific patient subgroups who might benefit.

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