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Updated: Jul 18, 2026

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Published on: April 18, 2025
Metastatic signet ring adenocarcinoma: an unusual cause of cardiac constriction
Ather Anis1, Rajeev L Narayan, Suraj Kapa
1Department of Medicine, Division of Cardiovascular Diseases, New Jersey Medical School, University Heights, Newark, NJ 07103, USA.
Abstract:
Pericardial constriction secondary to metastatic adenocarcinoma is exceedingly rare. We present the first recorded case of pericardial constriction secondary to metastatic signet-ring mucinous adenocarcinoma diagnosed by echocardiography. The cornerstones of echocardiographic diagnosis of constriction are the following: interventricular septal bounce phasic with respiration, M-mode recordings of the inferior vena cava, and the characteristic Doppler velocity patterns recorded from the mitral valve, hepatic veins, and mitral annulus.
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