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Updated: Jul 18, 2026
Murine Bilateral Renal Lymphadenectomy
Published on: December 30, 2025
Intrapulmonary lymph node metastasis and renal cell carcinoma
Jalal Assouad1, Marc Riquet, Pascal Berna
1Service de Chirurgie Thoracique, Hôpital Européen Georges Pompidou, 20 rue Leblanc, 75908 Paris, Cedex 15, France.
Intrapulmonary lymph node metastasis is a rare recurrence after kidney cancer surgery. Surgical resection of these metastases can confirm diagnosis and may be a treatment option.
Area of Science:
- Oncology
- Thoracic Surgery
- Nephrology
Background:
- Renal cell carcinoma (RCC) is a common kidney cancer.
- Nephrectomy is a standard surgical treatment for RCC.
- Intrapulmonary lymph node metastasis is an unusual pattern of RCC recurrence.
Observation:
- Two male patients developed intrapulmonary lymph node metastasis 2 and 4 years post-nephrectomy.
- Both patients underwent surgery for the recurrence.
- Surgical findings included station 7 lymph node metastases and positive pleural lavage cytology.
Findings:
- The recurrence likely originates from the thoracic duct.
- Surgical resection confirmed the diagnosis of intrapulmonary lymph node metastasis.
- One patient survived 2 years, and the other remained disease-free at 33 months post-surgery.
Implications:
- Surgical resection may be a viable treatment for this specific RCC recurrence.
- Early diagnosis and intervention are crucial for patient outcomes.
- Further research into the mechanisms of thoracic duct metastasis in RCC is warranted.
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