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Submandibular ectopic thyroid gland.

Juergen Zieren1, Marco Paul, Mark Scharfenberg

  • 1Department of General, Visceral, Vascular and Thoracic Surgery, Universitätsmedizin Berlin, Charité Campus Mitte, Humboldt University of Berlin, Charitéplatz 1, 10117 Berlin, Germany. juergen.zieren@charite.de

The Journal of Craniofacial Surgery
|November 23, 2006
PubMed
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Ectopic thyroid glands are rare, typically found in the neck. This case highlights a submandibular ectopic thyroid, emphasizing the need for physician awareness and thorough diagnosis for this unusual presentation.

Area of Science:

  • Endocrinology
  • Surgical Pathology
  • Head and Neck Surgery

Background:

  • Ectopic thyroid tissue is a rare congenital anomaly, most commonly located in the cervical midline.
  • While rare, ectopic thyroid tissue can occur in various extrathyroidal anatomical sites.

Observation:

  • An 81-year-old female presented with a right-sided submandibular swelling.
  • Fine-needle aspiration (FNA) biopsy indicated benign ectopic thyroid tissue.
  • Surgical resection of the submandibular mass was performed.

Findings:

  • Histological examination confirmed the presence of ectopic thyroid tissue in the submandibular region.
  • Postoperative thyroxine substitution therapy was initiated as this represented the patient's only functional thyroid tissue.

Related Experiment Videos

  • A literature review identified 18 previously reported cases of submandibular ectopic thyroid glands.

    • Implications:

    • Submandibular swelling should prompt consideration of ectopic thyroid tissue in the differential diagnosis.
    • Accurate preoperative diagnosis and surgical management are crucial for favorable outcomes in ectopic thyroid gland cases.
    • Physicians must be aware of the diagnostic and therapeutic challenges posed by ectopic thyroid glands in unusual locations.