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Updated: Jul 18, 2026

Accessing the Cytotoxicity and Cell Response to Biomaterials
Published on: July 8, 2021
Biological response of pulps submitted to different capping materials
André Luiz Fraga Briso1, Vanessa Rahal, Sandra Rahal Mestrener
1Department of Restorative Dentistry, School of Dentistry of Araçatuba, State University of São Paulo.
Mineral trioxide aggregate (MTA) shows a higher success rate for pulp capping than calcium hydroxide, reducing infection and necrosis. This dental procedure protects vital pulp tissue for better oral health outcomes.
Area of Science:
- Dentistry
- Biomaterials Science
Background:
- Pulp capping aims to preserve dental pulp vitality and function after exposure.
- Mineral trioxide aggregate (MTA) and calcium hydroxide are common capping agents.
Purpose of the Study:
- To compare the efficacy of MTA versus calcium hydroxide for direct pulp capping in dogs.
Main Methods:
- Thirty-seven dog teeth underwent pulp exposure and capping with either MTA or calcium hydroxide.
- Cavities were sealed, and specimens analyzed via optic microscopy after 60 days.
Main Results:
- MTA demonstrated a superior success rate compared to calcium hydroxide.
- Lower incidences of infection and pulp necrosis were observed with MTA.
Conclusions:
- MTA is a more effective material for direct pulp capping, promoting better healing and reducing adverse outcomes.
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