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Cardiovascular complications of pediatric chronic kidney disease

Mark M Mitsnefes1

  • 1Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA. mark.mitsnefes@cchmc.org

Pediatric Nephrology (Berlin, Germany)
|November 23, 2006
PubMed

Insights

Cardiovascular disease (CVD) is a major cause of death in adults with chronic kidney disease (CKD). This review focuses on cardiac risks, mortality, and morbidity in children with CKD.

Area of Science:

  • Pediatric Nephrology
  • Cardiovascular Medicine
  • Public Health

Background:

  • Cardiovascular disease (CVD) is a leading cause of mortality in adult chronic kidney disease (CKD).
  • Exceptionally high CVD mortality rates are observed in young adults with CKD.
  • Emerging data reveal the presence of cardiovascular complications in children with CKD.

Purpose of the Study:

  • To review the current literature on cardiac risk factors in pediatric CKD patients.
  • To summarize the existing data on cardiovascular mortality in children with CKD.
  • To outline the cardiovascular morbidity associated with CKD in pediatric populations.

Main Methods:

  • Comprehensive literature search of relevant databases.
  • Systematic review of studies focusing on pediatric CKD and cardiovascular outcomes.
  • Analysis of data on cardiac risk factors, mortality, and morbidity.

Main Results:

  • Cardiovascular complications are evident in children with CKD.
  • Specific cardiac risk factors contributing to morbidity and mortality in this population require further investigation.
  • Data on long-term cardiovascular outcomes in pediatric CKD are limited.

Conclusions:

  • Children with CKD face significant cardiovascular risks.
  • Early identification and management of cardiac risk factors are crucial in pediatric CKD.
  • Further research is needed to fully understand and address cardiovascular disease in children with CKD.

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