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[Relationship between pathological changes of coronary artery and severity of Xiongbi syndrome]

Li-heng Guo1, Min-zhou Zhang, Fang Yan

  • 1Provincial Hospital of Traditional Chinese Medicine, Guangzhou. guolh782@sohu.com

Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine
|November 24, 2006
PubMed

Insights

This study found no direct link between the severity of Xiongbi syndrome (angina pectoris) and coronary artery disease extent. Traditional Chinese medicine assessments for Xiongbi syndrome did not correlate with coronary angiography findings.

Area of Science:

  • Cardiology
  • Traditional Chinese Medicine
  • Integrative Medicine

Background:

  • Xiongbi syndrome, a term used in Traditional Chinese Medicine (TCM) for angina pectoris, is often assessed for severity.
  • The correlation between TCM-based severity grading and objective measures of coronary artery disease (CAD) requires investigation.

Purpose of the Study:

  • To investigate the relationship between the severity of Xiongbi syndrome, as defined by clinical principles, and the outcomes of coronary angiography (CAG).

Main Methods:

  • Severity of Xiongbi syndrome was graded in 207 patients using the "Guiding principle for clinical study on new traditional Chinese medicine in treating Xiongbi (angina pectoris)".
  • Patients underwent coronary angiography (CAG) using the Judkins method.
  • Statistical analysis was performed to assess the relationship between Xiongbi syndrome severity and CAG findings.

Main Results:

  • While abnormal electrocardiogram (ECG) rates differed significantly between patients with no coronary lesions and those with single or double-branch lesions (P < 0.05), no significant difference was observed for multiple-branch lesions.
  • A significant difference in Xiongbi syndrome severity was noted between patients with normal coronary arteries and those with lesions in different branches (P < 0.01).
  • Interestingly, milder Xiongbi syndrome presentations were most common in patients with multiple-branch coronary lesions, with severity decreasing as lesion complexity increased.

Conclusions:

  • The severity of Xiongbi syndrome, as assessed by the TCM principle, does not show a positive correlation with the severity of coronary artery disease.
  • These findings suggest that TCM symptom severity may not directly reflect the anatomical extent of coronary atherosclerosis.
Abstract

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