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Related Experiment Videos

Systemic blastomycosis in a horse.

Julia H Wilson1, Erik J Olson, Edward W Haugen

  • 1Division of Large Animal Medicine , Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN 55108, USA.

Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
|November 24, 2006
PubMed
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A rare case of blastomycosis, a fungal infection caused by Blastomyces dermatitidis, was diagnosed in a horse. This progressive multisystemic disease presented with unusual mammary gland involvement and widespread thrombi.

Area of Science:

  • Veterinary Mycology
  • Equine Infectious Diseases

Background:

  • Blastomycosis, caused by the fungus Blastomyces dermatitidis, is endemic in certain regions but rarely reported in horses.
  • This case involves a 17-year-old Quarter horse broodmare with a history of unsuccessful antibiotic treatment for mastitis.

Observation:

  • The mare presented with progressive, multisystemic signs including exudative cutaneous lesions, weight loss, pleural effusion, and lung lesions.
  • Clinical diagnosis of blastomycosis was suspected based on yeast bodies in cutaneous exudate.
  • Necropsy revealed extensive pyogranulomas in mammary gland, skin, lungs, and other tissues, with thrombi in major blood vessels.

Findings:

  • Blastomyces dermatitidis was confirmed through fungal culture from multiple tissues, including mammary gland and lungs.

Related Experiment Videos

  • Histopathology showed pyogranulomatous inflammation and fungal organisms in various organs.
  • Unique features included extensive mammary gland involvement and multiple sites of thrombosis.

    • Implications:

    • Highlights the potential for blastomycosis misdiagnosis in horses due to its rarity.
    • Emphasizes the importance of considering fungal infections in horses with progressive, unexplained clinical signs.
    • This case expands the understanding of Blastomyces dermatitidis manifestations in equine species.