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Related Concept Videos

Retrovirus Life Cycles01:10

Retrovirus Life Cycles

Retroviruses have a single-stranded RNA genome that undergoes a special form of replication. Once the retrovirus has entered the host cell, an enzyme called reverse transcriptase synthesizes double-stranded DNA from the retroviral RNA genome. This DNA copy of the genome is then integrated into the host’s genome inside the nucleus via an enzyme called integrase. Consequently, the retroviral genome is transcribed into RNA whenever the host’s genome is transcribed, allowing the retrovirus to...
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...

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Articles linked to this work by shared authors, journal, and citation graph.

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[A cross-sectional case study of human immunodeficiency virus and tuberculosis co-infection in mainland China].

Zhonghua nei ke za zhi·2007
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T-cell response of advanced aids patients after highly active antiretroviral therapy.

Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih·2006
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[Study on the distribution of human immunodeficiency virus-1 subtypes in different regions of China and mother-to-child transmission].

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Virological and immunological outcomes in HIV-1-infected Chinese patients treated with a combination of Efavirenz and Indinavir for 48 weeks.

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[Study on the epidemiology and distribution of human immunodeficiency virus-1 and hepatitis C virus infection among intravenous drug users and illegal blood donors in China].

Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi·2003

Related Experiment Video

Updated: Jul 18, 2026

Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays
13:58

Amplifying and Quantifying HIV-1 RNA in HIV Infected Individuals with Viral Loads Below the Limit of Detection by Standard Clinical Assays

Published on: September 26, 2011

[Clinical and basic researches on HIV/AIDS].

Yun-zhen Cao1

  • 1AIDS Research Center, CAMS and PUMC, Beijing 100730, China. dryunzhencao@yahoo.com

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
|November 24, 2006
PubMed
Summary

Human immunodeficiency virus (HIV) is primarily sexually transmitted. While highly active antiretroviral therapy (HAART) has advanced treatment, challenges like drug resistance and global access remain critical for HIV/AIDS prevention and care.

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Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model
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Comprehensive & Cost Effective Laboratory Monitoring of HIV/AIDS: an African Role Model

Published on: October 31, 2010

Area of Science:

  • Infectious Diseases
  • Virology
  • Immunology

Context:

  • Sexual transmission accounts for 85% of global human immunodeficiency virus (HIV) infections.
  • Behavioral interventions and condom promotion have shown success in HIV prevention.
  • Highly active antiretroviral therapy (HAART) has revolutionized HIV-1 infection management.

Purpose:

  • To review the current landscape of HIV/AIDS prevention and treatment.
  • To highlight advances in HAART and its impact on viral load and CD4+ T cell counts.
  • To identify future challenges in HIV/AIDS management and research.

Summary:

  • HAART effectively reduces plasma viral load and improves CD4+ T cell counts in HIV-1 patients.
  • Despite HAART's success, challenges persist, including drug resistance and adverse events.
  • Future efforts must address new therapies, coinfections (liver disease, tuberculosis), resource-limited settings, and comprehensive HIV/AIDS prevention.

Impact:

  • Advances in HAART offer improved quality of life and prognosis for individuals with HIV.
  • Addressing drug resistance and coinfections is crucial for long-term HIV management.
  • Global collaboration is essential to overcome challenges in resource-limited countries and achieve further success in HIV/AIDS prevention and treatment.