[Coinfection with HBV and HCV in 128 AIDS patients infected through blood transmission]
Related Experiment Video
Updated: Jul 18, 2026

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
Published on: May 10, 2022
Yun He1, Qing-xia Zhao, Ying-jie Ren
1Department of AIDS, the Sixth People's Hospital of Zhengzhou, Zhengzhou 450015, China. yuerhe@163.com
Objective:
To analyze the clinical features of 128 acquired immunodeficiency syndrome (AIDS) patients infected through blood transmission who were coinfected with hepatitis B virus (HBV) and hepatitis C virus (HCV).
Methods:
The prevalence, liver functions, and some immunological profiles of 128 AIDS patients coinfected with HBV and HCV were retrospectively analyzed.
Results:
Among the 128 AIDS patients, 107 (83.6%) were coinfected with HCV, among which 40 (31.3%) patients had abnormal liver functions or liver damage and 15 (11.7%) patients experienced hepatitis symptoms. Three (2.3%) AIDS patients were singly coinfected with HBV, and all of them had abnormal liver functions and hepatitis symptoms. Seven (5.5%) patients were coinfected with HIV/HCV/HBV and none of them had abnormal liver functions or hepatitis symptoms. Eleven (8.6%) patients were only infected with HIV.
Conclusions:
The prevalence of blood-transmitted HIV patients coinfected with HCV is higher than with HBV. The clinical outcomes of HIV coinfection with HCV and HBV are different.
Related Concept Videos
Hepatitis
Viral Hepatitis I: Introduction
Sexually Transmitted Infections
Retrovirus Life Cycles
Cytomegalovirus Disease
Immunodeficiency Diseases
There are three main causes of immunodeficiency disorders...
