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Updated: Jul 18, 2026

The Quantification of Injectability by Mechanical Testing
Published on: May 13, 2020
[Preparation and characterization of a new injectable bone substitute-carrageenan/nano-hydroxyapatite/collagen]
1Department of Material Science and Engineering, Tsinghua University, Beijing 100084, China.
Objective:
To develop a new injectable biomaterial carrageenan/nano-hydroxyapatite/collagen (nHAC/Carr) for bone surgery and characterize it.
Methods:
nHAC/Carr was developed by filling carrageenan with nano-hydroxyapatite/collagen (nHAC) granules.
Results:
It was found that nHAC/Carr had similar X-ray diffraction patterns with that of nHAC. Fourier transform infrared spectroscopy showed that carrageenan did not change its structure in nHAC/Carr. The rheological behavior of nHAC/Carr was the same as carrageenan. The scanning electron microscopy and porosity analysis showed that nHAC/Carr had porous structure and its porosity was about 90%.
Conclusion:
The biomaterial nHAC/Carr may be used as an injectable bone substitute.

