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Related Experiment Video

Updated: Jul 18, 2026

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

Published on: February 23, 2017

Calcium modulates interactions between bacteria and hydroxyapatite.

S C Venegas¹, J M Palacios, M C Apella

¹Centro de Referencia para Lactobacilos (CERELA), Chacabuco 145, 4000, San Miguel de Tucumán, Tucumán, Argentina.

Journal of Dental Research

|November 24, 2006

Summary

Calcium (Ca2+) concentration significantly impacts bacterial adhesion to hydroxyapatite, with effects varying by bacterial strain and surface properties. This finding is crucial for understanding biomaterial interactions.

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Calcium Carbonate Formation in the Presence of Biopolymeric Additives

Calcium Carbonate Formation in the Presence of Biopolymeric Additives

Published on: May 14, 2019

Area of Science:

Biomaterials Science
Microbiology
Surface Chemistry

Background:

Bacterial adhesion to biomaterials like hydroxyapatite is influenced by surface characteristics.
The role of aqueous medium composition, specifically ion concentration, on this adhesion is less understood.

Purpose of the Study:

To investigate the effect of calcium ion (Ca2+) concentration on the adhesion of Streptococcus mutans and three Lactobacillus species to hydroxyapatite.
To correlate adhesion changes with bacterial strain-specific surface properties.

Main Methods:

Studied adhesion of Streptococcus mutans, Lactobacillus fermentum, Lactobacillus salivarius, and Lactobacillus casei on powdered hydroxyapatite.
Varied the calcium ion (Ca2+) concentration in the aqueous medium.
Assessed bacterial surface properties including hydrophobicity and electrophoretic mobility.

Main Results:

Adhesion varied significantly with Ca2+ concentration, depending on the bacterial strain.
Increased Ca2+ enhanced adhesion for Lactobacillus fermentum, Lactobacillus salivarius, and Streptococcus mutans (at low Ca2+).
Lactobacillus casei showed high adhesion independent of Ca2+, with minimal ion effect.

Conclusions:

Calcium ions mediate bacterial adhesion to hydroxyapatite, with strain-specific responses.
Bacterial hydrophobicity and surface electrical properties influence Ca2+-dependent adhesion.
Findings provide insights into controlling bacterial colonization on hydroxyapatite biomaterials.