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Immunological aspects of inhibitor development.

M T Reding1

  • 1Division of Hematology, Oncology and Transplantation, Hemophilia and Thrombosis Center, University of Minnesota, Minneapolis, MN, USA. redin002@umn.edu

Haemophilia : the Official Journal of the World Federation of Hemophilia
|November 25, 2006
PubMed
Summary

Inhibitor antibodies are a serious complication of factor replacement therapy. Understanding the immune response to factor VIII (FVIII) and regulatory T-cells is key to preventing inhibitor formation in haemophilia.

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