Regular exercise attenuated lipid peroxidation in adolescents with Down's syndrome
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Francisco Javier Ordonez1, Manuel Rosety-Rodriguez
1Sport Medicine School, Virgen del Saliente s/n, 11100 San Fernando, Cádiz, Spain.
Objectives:
This study was designed to ascertain whether regular exercise may attenuate lipid peroxidation in adolescents with Down's syndrome.
Materials And Methods:
Thirty-one male adolescents with Down's syndrome performed a 12-week training program, 3 days/week at a work intensity of 60-75% of peak heart rate (HRmax=194.5-[0.56 age]). Plasmatic malondialdehyde (MDA) was determined by high performance liquid chromatography (HPLC).
Results:
When compared to baseline, MDA content was decreased significantly.
Conclusion:
Regular exercise significantly decreased lipoperoxidation in Down's syndrome.
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