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Updated: Jul 18, 2026
06:01
A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Thrombosis in infants and children
Reinhard Schneppenheim1, Jeanette Greiner
1University Medical Center Hamburg-Eppendorf, Department of Pediatric Hematology and Oncology, Martinistrasse 52, 20246 Hamburg, Germany. schneppenheim@uke.de
Hematology. American Society of Hematology. Education Program
|November 25, 2006
Summary
Recent advances improve understanding of pediatric thromboembolism causes and risk factors. However, clear guidelines for interventions like anticoagulation and thrombolysis are still needed for better treatment and outcomes.
Area of Science:
- Pediatric Hematology
- Thrombosis and Hemostasis
Background:
- Significant progress in understanding pediatric thromboembolism in the last decade.
- Identification of numerous acquired and hereditary thrombotic risk factors.
- These factors influence therapeutic decisions, prognosis, and risk of recurrence.
Purpose of the Study:
- To describe the causes, clinical presentation, and management of thrombosis in children.
- Focus on clinically relevant conditions in neonates, infants, and older children.
- Address the need for better-defined indications for therapeutic interventions.
Main Methods:
- Review of current understanding of pediatric thromboembolism.
- Analysis of identified acquired and hereditary thrombotic risk factors.
- Discussion of therapeutic interventions including thrombolysis and anticoagulation.
Main Results:
- Advances in identifying causes and risk factors for pediatric thrombosis.
- Recognition of the impact of these factors on patient outcomes.
- Current lack of well-defined indications for specific therapeutic interventions.
Conclusions:
- While understanding of pediatric thromboembolism has grown, therapeutic guidelines require further development.
- The article provides a comprehensive overview of thrombosis in pediatric populations.
- Further research is needed to establish clear indications for interventions like anticoagulation and thrombolysis.
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