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Crystal Growth: Principles of Crystallization01:25

Crystal Growth: Principles of Crystallization

Crystallization is a phase transformation process in which crystals are precipitated from a supersaturated solution or formed from other sources. During crystallization, atoms or molecules arrange themselves into a well-defined, rigid crystal lattice to minimize energy.
Initiating crystallization involves manipulating the concentration of the solute and the temperature of the solution. Since crystal growth occurs when the ratio of concentration and solubility of the solute in the solvent – the...

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Growing Protein Crystals with Distinct Dimensions Using Automated Crystallization Coupled with In Situ Dynamic Light Scattering
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Developing quantitative, multiscale models for microgravity crystal growth.

Jeffrey J Derby1, Yong-Il Kwon, Arun Pandy

  • 1Department of Chemical Engineering & Materials Science and Minnesota Supercomputer Institute, University of Minnesota, Minneapolis, Minnesota 55455-0132, USA. derby@umn.edu

Annals of the New York Academy of Sciences
|November 25, 2006
PubMed
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Microgravity crystal growth enhances understanding of melt processes. New multiscale models are needed for accurate simulation of transport phenomena and phase changes in crystal growth.

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Area of Science:

  • Materials Science
  • Physics
  • Space Science

Background:

  • Microgravity crystal growth experiments have significantly advanced the understanding of melt crystal growth.
  • Interpreting and optimizing these experiments requires sophisticated modeling approaches.

Purpose of the Study:

  • To provide a historical overview of microgravity crystal growth.
  • To discuss the development of models for interpreting and optimizing microgravity crystal growth.
  • To highlight the need for advanced multiscale modeling.

Main Methods:

  • Review of historical microgravity crystal growth studies.
  • Discussion of mathematical models and numerical algorithms for multiscale phenomena.
  • Focus on continuum transport, phase-change, and system design.

Main Results:

  • Microgravity conditions offer unique insights into melt crystal growth.
  • Multiscale modeling is crucial for accurately representing complex phenomena.
  • Advanced models are necessary for predictive capabilities in crystal growth.

Conclusions:

  • Microgravity research has been pivotal in understanding melt crystal growth.
  • Developing realistic, multiscale models is essential for future advancements.
  • These models must integrate transport phenomena, phase changes, and system design.