Related Experiment Video
Updated: Jul 18, 2026

A Novel Approach to Assess Motor Outcome of Deep Brain Stimulation Effects in the Hemiparkinsonian Rat: Staircase and Cylinder Test
Published on: May 31, 2016
[Electrostimulation of a subthalamic nuclear area in Parkinson's disease]
Abstract:
The paper presents the results of application of chronic electrostimulation of the subthalamic nucleus in 15 patients with the akinetic-rigid form of Parkinson's disease. Standard UPDRS, Schwab and England, Hoehn and Yahr, and PDQ-39 rating scales were used for the clinical evaluation of motor disorders. The patients were examined before and 6 months after surgery with ON-stimulation in OFF and ON-medication. Positive results as better life quality, ameliorated motor disorders, and fewer complication of drug therapy with a two-fold reduction in the daily dose of L-dopa were obtained in the vast majority of patients (n = 14).
Related Concept Videos
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...
Parkinson Disease ll: Pathophysiology
Neural Regulation

