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'Complementary ENT': a systematic review of commonly used supplements
P D Karkos1, S C Leong, A K Arya
1Department of Otolaryngology, University Hospital Aintree, Liverpool, UK. pkarkos@aol.com
The Journal of Laryngology and Otology
|November 28, 2006
Summary
Spirulina shows promise for allergic rhinitis, and Vertigoheel for vertigo, but more research is needed. Ginkgo biloba is ineffective for tinnitus, and evidence for multivitamins in sinus issues is limited.
Area of Science:
- Otolaryngology
- Complementary Medicine
- Evidence-Based Medicine
Background:
- The use of complementary supplements is prevalent in otolaryngology.
- Evidence supporting these supplements often lacks rigorous scientific validation.
Purpose of the Study:
- To systematically review the evidence for four common complementary supplements used in otolaryngology: spirulina, Ginkgo biloba, Vertigoheel, and nutritional supplements (cod liver oil, multivitamins, pineapple enzyme).
Main Methods:
- A systematic review of English and foreign language literature was conducted.
- Inclusion criteria focused on in vivo human studies.
- Exclusion criteria included animal trials, in vitro studies, case reports, and other forms of alternative medicine.
Main Results:
- Spirulina demonstrated positive effects in allergic rhinitis and mucosal immunity in human studies.
- Ginkgo biloba showed no evidence of efficacy for tinnitus.
- Vertigoheel was found to be effective for vertigo, comparable to standard treatments.
- Multivitamins and cod liver oil showed potential benefits for sinusitis and otitis media in pediatric studies.
- Bromelain (pineapple enzyme) accelerated recovery in acute sinusitis.
Conclusions:
- Spirulina and Vertigoheel have promising evidence for allergic rhinitis and vertigo, respectively, warranting larger trials.
- Ginkgo biloba is not recommended for tinnitus.
- Limited evidence supports multivitamins for sinus symptoms, requiring further investigation.
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