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Recombinant factor VIIa in massive postpartum haemorrhage

D Karalapillai1, P Popham

  • 1Department of Anaesthesia, Royal Women's Hospital, Carlton, Victoria, Australia.

International Journal of Obstetric Anesthesia
|November 28, 2006
PubMed

Massive postpartum haemorrhage is a major cause of maternal and fetal morbidity and mortality. Management mainstays include transfusion therapy, uterotonic agents and surgery. The "off label" use of recombinant activated factor VII appears to have an evolving role in the management of massive postpartum haemorrhage refractory to conventional treatments. The current literature is reviewed.

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