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Updated: Jul 18, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Pulmonary atresia with intact ventricular septum: initial management
Kelly M McLean1, Jeffrey M Pearl
1Division of Cardiothoracic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, USA.
Catheter-based therapy for pulmonary atresia with intact ventricular septum rarely avoids surgery. Most infants still require surgical intervention for pulmonary blood flow, highlighting the need for further management strategies.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Interventional Cardiology
Background:
- Pulmonary atresia with intact ventricular septum (PAIVS) presents suboptimal outcomes.
- Initial management strategies for PAIVS are debated.
- This study evaluates catheter-based therapy's impact on early surgical intervention needs.
Purpose of the Study:
- To assess the efficacy of catheter-based interventions in neonates with PAIVS.
- To determine if catheter-based therapy reduces the necessity for early surgical procedures.
- To analyze outcomes following catheter-based interventions in PAIVS patients.
Main Methods:
- Retrospective chart review of 25 neonates with PAIVS (1999-2005).
- Analysis of initial interventions: catheter-based therapy vs. operative procedures.
- Evaluation of technical success, complications, and subsequent surgical requirements.
Main Results:
- 56% of patients initially received catheter-based therapy (valvotomy).
- Adequate valvotomy achieved in 79%, but 64% required surgery post-catheterization.
- Only 36% weaned from prostaglandins without surgery; 3 of 23 treated patients avoided infancy operation.
Conclusions:
- Balloon valvotomy for PAIVS seldom eliminates the need for surgical pulmonary blood flow.
- Additional procedures like shunts or stenting are frequently required post-catheterization.
- Catheter-based therapy alone is insufficient to obviate surgical intervention in most PAIVS cases.
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