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Published on: March 8, 2015
Deep brain stimulation in movement and psychiatric disorders
David E Hardesty1, Harold A Sackeim
1Department of Biological Psychiatry, New York State Psychiatric Institute, New York, New York 10032, USA. dhardesty@neuro.columbia.edu
Biological Psychiatry
|November 28, 2006
Summary
Deep brain stimulation (DBS) offers adjustable, reversible therapy for brain conditions. This invasive electromagnetic technique shows efficacy in movement disorders and potential for psychiatric conditions in treatment-resistant patients.
Area of Science:
- Neurology
- Neurosurgery
- Biomedical Engineering
Background:
- Deep brain stimulation (DBS) is a focal electromagnetic brain stimulation therapy.
- It involves a pulse generator and microelectrode for targeted brain tissue stimulation.
- DBS offers an adjustable, reversible, and specific therapeutic approach.
Purpose of the Study:
- To review the established efficacy and emerging applications of DBS.
- To highlight DBS as a potential option for treatment-resistant neurological and psychiatric disorders.
Main Methods:
- Utilizes a subcutaneous pulse generator connected to a microelectrode.
- Stimulation is delivered to circumscribed brain tissue within a specific target.
- Therapy is adjustable, reversible, and specific to the patient's needs.
Main Results:
- Established efficacy in various movement disorders.
- Promising results reported for Tourette syndrome, obsessive-compulsive disorder, and major depression.
- Demonstrates potential as a therapeutic option for severe, treatment-resistant cases.
Conclusions:
- DBS is a viable treatment for specific neurological and psychiatric conditions.
- It offers a valuable option for patients with limited therapeutic alternatives and poor prognoses.
- Further research into DBS mechanisms may enhance its application.
