Related Experiment Video
Updated: Jul 18, 2026

System for Focal, Closed-System Central Nervous System Injury
Published on: November 29, 2024
Care of central nervous system injuries
1Department of Neurosurgery, University of Washington, Harborview Medical Center, Box 359766, 325 Ninth Avenue, Seattle, WA 98104-2499, USA. chesnutr@u.washington.edu
Abstract:
The primary method of improving outcome from traumatic brain injury is through avoiding secondary insults to the injured brain. Although surgery is important, most management is critical care. Evidence-based guidelines continue to be developed to assist in directing care. With modern monitoring systems, a physiologic-based approach is increasingly applicable, allowing focused treatment for intracranial hypertension and ischemia. It is important to balance and integrate the care of the injured brain into the overall care of the polytrauma patient.
More Related Videos
Related Concept Videos
Traumatic Brain Injury l: Introduction
Secondary Spinal Cord Injury llI: Pathophysiology
Spinal Cord Injury ll: Pathophysiology
Neurogenesis and Regeneration of Nervous Tissue
Cerebrospinal Fluid
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain.
Drug Delivery: Parenteral Route
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...

