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QSCOP--SCOP quantified by structural relationships.

Stefan J Suhrer1, Markus Wiederstein, Manfred J Sippl

  • 1Center of Applied Molecular Engineering, Department of Bioinformatics, Division of Molecular Biology, University of Salzburg, 5020 Salzburg, Austria.

Bioinformatics (Oxford, England)
|November 28, 2006
PubMed
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The Structural Classification Of Proteins (SCOP) database now includes quantified structural information. This enhancement allows for a deeper understanding of structural diversity within protein families and the broader SCOP hierarchy.

Area of Science:

  • Protein science
  • Bioinformatics
  • Structural biology

Background:

  • The Structural Classification Of Proteins (SCOP) database is a key resource in bioinformatics and protein science.
  • SCOP's classification rules are flexible, preserving expert-identified details.
  • Quantified SCOP (QSCOP) is accessible via a public web service.

Purpose of the Study:

  • To integrate quantified structural information into classic SCOP Families.
  • To analyze and comment on the structural diversity within the SCOP hierarchy.

Main Methods:

  • Endowing classic SCOP Families with quantified structural data.
  • Analyzing structural information within the SCOP hierarchy.

Main Results:

Related Experiment Videos

  • SCOP Families have been enriched with quantitative structural data.
  • Insights into the structural diversity across the SCOP hierarchy have been provided.

Conclusions:

  • The integration of quantified structural information enhances the utility of the SCOP database.
  • QSCOP provides a valuable resource for studying protein structural diversity.