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[Gamna Gandy bodies: Features mimicking a mycotic disease. Two cases in the spleen]
Damien Ambrosetti1, Sandra Lassalle, Arthur N'Golet
1Laboratoire de Pathologie Clinique et Expérimentale, Hôpital Pasteur, BP 69, 06002 Nice Cedex.
Abstract:
We report the clinical and histopathological features of 2 cases of Gamna-Gandy bodies located in the spleen. The diagnosis was made by the presence of circumscribed nodules containing dark brown rod-shaped and "bamboo-shaped" fibrotic structures. These structures were positive with Perls and von Kossa staining. Differential diagnosis includes filamentous mycoses such as mucormycosis and phaeohyphomycosis. Gamna-Gandy nodules can be isolated or these bodies can be observed associated with another lesion, particularly, a tumor.
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