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Isolation, Culture, and Characterization of Dental Pulp Stem Cells from Human Deciduous and Permanent Teeth
Published on: May 17, 2024
[Dental extractions in children with congenital coagulation disorders: therapeutic protocol and results]
A Kaddour Brahim1, N Stieltjes, V Roussel-Robert
1Service de Chirurgie Maxillo-faciale et Stomatologie Pédiatriques, Hôpital Saint-Vincent-de-Paul, 74-82, avenue Denfert-Rochereau, 75014 Paris.
Introduction:
We report the results of our 10-year experience with a protocol of local hemostasis specifically elaborated for children with congenital bleeding disorders.
Material And Method:
Sixty-four dental extractions procedures were performed in 37 children. Local hemostasis was achieved with the CO2 laser at the site of extraction previously filled with regenerated oxidized cellulose. The site of extraction was then protected with thermomolded splint. The replacement therapy (hemostasis factor concentrates, platelet concentrates) was coordinated by the hematologist and restricted as much as possible.
Results:
160 decidual teeth and 23 permanent teeth were extracted. None of the children with minor bleeding deficiency received replacement therapy. Ten post-operative bleedings were recorded but none was considered severe.
Discussion:
This protocol characterized by the use of CO2 laser for the hemostasis gave satisfaction in children. The rare and minor post-operative bleedings could be explained by multiple extractions, local infection and/or children's anxiety. This strategy requires a close cooperation between the stomatologist and the hematologist in order to determine the optimal therapeutic management.
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