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Updated: Jul 18, 2026

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
Published on: January 23, 2026
[Infradiaphragmatic extralobar pulmonary sequestration]
1Klinik für Strahlenheilkunde, Abt. Päd. Radiologie, Charité Universitätsmedizin Berlin. thomas.riebel@charite.de
Insights
Infradiaphragmatic extralobar pulmonary sequestration (IEPS) in infants can be reliably diagnosed using ultrasound (US). Characteristic findings on prenatal and postnatal US suggest IEPS, which often shows benign, spontaneous regression, supporting conservative management with US monitoring.
Area of Science:
- Pediatric radiology
- Medical imaging
- Congenital anomalies
Context:
- Infradiaphragmatic extralobar pulmonary sequestration (IEPS) is a rare congenital lung malformation.
- Accurate prenatal and postnatal diagnosis is crucial for appropriate management.
- Ultrasound (US) is a widely available and non-invasive imaging modality.
Purpose:
- To highlight the characteristic imaging findings of IEPS on ultrasound (US).
- To evaluate the role of US in diagnosing IEPS in infants.
- To correlate imaging findings with clinical outcomes.
Summary:
- Four infants with suspected IEPS were evaluated using prenatal and postnatal US, with MRI in two cases.
- Characteristic hyperechoic suprarenal masses with cystic components were identified on US.
- Two patients underwent surgery, while two were managed conservatively with US monitoring, showing spontaneous regression.
Impact:
- Characteristic US findings allow for reliable diagnosis of IEPS.
- Understanding the benign, self-regressing nature of IEPS supports conservative management.
- US monitoring is effective for suspected IEPS lesions, potentially avoiding unnecessary surgery.
Purpose:
To demonstrate characteristic imaging findings in infradiaphragmatic extralobar pulmonary sequestration (IEPS) with special emphasis on ultrasound (US).
Materials And Methods:
The imaging material (pre- and postnatal US in all cases, magnetic resonance imaging (MRI) in 2 cases) for 4 infants (3 girls, 1 boy) was reviewed. 2 patients underwent surgery (after birth and at 4 months of age, respectively) and the diagnosis of IEPS was confirmed. The other 2 patients were monitored conservatively using US for up to 15 months.
Results:
All 4 left-side suprarenal masses exhibited the same characteristic sono-morphology, leading to the suspected diagnosis of IEPS. The masses were small (max. 10 ml), hyperechoic with cystic components and without calcifications, well demarcated and separate from the normal kidney and the suprarenal gland, and without any change in prenatal and directly postnatal size. Doppler US showed low-grade perfusion in all cases and an aberrant systemic artery originating from the abdominal aorta in 2 cases. MRI did not add any fundamental information. Despite the suspected imaging diagnosis of IEPS and negative urinalyses for neuroblastoma, 2 patients underwent surgery for histological confirmation. The lesions in the other 2 patients were monitored via US. A complete disappearance after 4 months in one patient and a continuous decrease in size over 15 months in the other patient were documented.
Conclusion:
Based on the characteristic findings of prenatal and postnatal US, IEPS can be diagnosed reliably. With the knowledge of its benign spontaneously regressing behavior, suspected suprarenal lesions should be treated conservatively via US monitoring.
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Clinical Manifestations:

