Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Accessory Structures of the Skin: Nails01:05

Accessory Structures of the Skin: Nails

Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
Local Anesthetics: Adverse Effects01:12

Local Anesthetics: Adverse Effects

While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
Effects of Chemicals: Overview01:27

Effects of Chemicals: Overview

Drugs, encompassing various chemical compounds from natural sources, lab synthesis, or genetic engineering, elicit different biological responses in living organisms. Some of these responses are desirable or therapeutic, while others are undesirable. The primary goal of administering a drug is to achieve a therapeutic effect, that is, to address a specific disease or health condition. Any concurrent effects outside of this therapeutic outcome are considered undesirable. These undesirable...
Vitamins01:30

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Toxic Reactions: Overview01:26

Toxic Reactions: Overview

When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Modern definitions of periungual pigmentation (Hutchinson sign): Results of an expert opinion consensus conference.

Journal of the American Academy of Dermatology·2025
Same author

Squamous cell carcinoma of the nail apparatus: Histopathology and immunohistochemistry correlation study.

Journal of cutaneous pathology·2024
Same author

Green nail: Etiology and treatment of chloronychia.

Hand surgery & rehabilitation·2024
Same author

Nail cosmetology.

Hand surgery & rehabilitation·2024
Same author

Three atypical/malignant onychopapillomas in a 52-case series with immunohistochemical study.

Journal of cutaneous pathology·2023
Same author

Bothnian Palmoplantar Keratoderma: Further Delineation of the Associated Phenotype.

Genes·2022

Related Experiment Video

Updated: Jul 18, 2026

Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
04:12

Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma

Published on: January 19, 2024

Side effects of nail cosmetics.

Robert Baran1, Josette André

  • 1Nail Disease Center, Cannes, France. baran.r@club-internet.fr

Journal of Cosmetic Dermatology
|November 30, 2006
PubMed
Summary

Nail cosmetics, including coatings and synthetic covers, can cause adverse reactions. These reactions range from local skin issues and distant contact dermatitis to systemic effects and infection risks.

Area of Science:

  • Dermatology
  • Cosmetic Science

Background:

  • Nail cosmetics include evaporative coatings, polymerizing coatings, and synthetic nail covers.
  • Adverse reactions are associated with various nail cosmetic applications.

Purpose of the Study:

  • To review the adverse reactions associated with different types of nail cosmetics.
  • To categorize the local, distant, systemic, and infection-related risks of nail cosmetic use.

Main Methods:

  • Literature review of adverse reactions to nail cosmetics.
  • Classification of reactions based on cosmetic type and reaction manifestation.

Main Results:

  • Evaporative coatings and polymerizing coatings can cause local reactions and distant contact dermatitis.

Related Experiment Videos

Last Updated: Jul 18, 2026

Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
04:12

Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma

Published on: January 19, 2024

  • Polymerizing coatings and synthetic covers are frequently linked to severe local reactions.
  • All nail cosmetic types carry potential risks including local and distant reactions, systemic effects, and infections.
  • Conclusions:

    • Nail cosmetics, regardless of type, can induce a spectrum of adverse reactions.
    • Understanding these risks is crucial for safe cosmetic nail product use and management of side effects.