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Updated: Jul 18, 2026

Swine Model of Biofilm Infection and Invisible Wounds
Published on: June 16, 2023
Surgical wound infection: epidemiology, pathogenesis, diagnosis and management
1Harvard Medical School, Boston MA, 02115, USA. rhrubin@partners.org
Abstract:
Surgical wound infection remains a significant problem following an operation, although surveillance for such infections remains a challenge exacerbated by early discharge and outpatient surgery. The risk of such infections is determined by technical problems with the operation, particularly bleeding, the amount of devitalized tissue created, and the need for drains within the wound, as well as such metabolic factors as obesity and diabetes. Perioperative antibiotic prophylaxis can decrease the incidence of such infections further, but a technically perfect operation is even more important.
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