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Defining and investigating occupational asthma: a consensus approach.

H C Francis1, C O Prys-Picard, D Fishwick

  • 1North West Lung Research Centre, Wythenshawe Hospital, Manchester, UK. Helen.C.Francis@manchester.ac.uk

Occupational and Environmental Medicine
|November 30, 2006
PubMed
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This study establishes a consensus definition for occupational asthma and outlines essential resources for specialist clinics. The findings aim to standardize the diagnosis and management of occupational asthma across the UK.

Area of Science:

  • Pulmonology
  • Occupational Medicine
  • Clinical Consensus

Background:

  • Lack of a universally agreed definition for occupational asthma hinders consistent diagnosis and management.
  • Guidance on essential resources for specialist occupational asthma services is currently insufficient.

Framework:

  • Developed a working definition for occupational asthma, encompassing sensitizer-induced and acute irritant-induced asthma (Reactive Airways Dysfunction Syndrome - RADS).
  • Defined acute irritant-induced asthma as a type of occupational asthma without latency or sensitization, following a single high exposure.
  • Proposed 'work-related asthma' as an umbrella term including occupational asthma, RADS, and aggravation of pre-existing asthma.

Implementation:

  • Utilized a modified RAND appropriateness method with a UK expert panel of clinicians.

Related Experiment Videos

  • Achieved consensus on key definitions and a framework of 18 essential resources for specialist services.
  • Resources include spirometry, peak flow monitoring, provocation challenges, and specific IgE testing.

    • Implications:

    • Aims to improve the uniformity of occupational asthma definition and investigation across the UK.
    • Provides a foundation for standardized care in specialist occupational asthma clinics.
    • Facilitates more consistent diagnosis and management strategies for patients with occupational asthma.