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Updated: Jul 18, 2026

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
Published on: December 9, 2016
Subcutaneous metastasis from esophageal cancer
Mohir H Hedeshian1, Xiaofei Wang, Bo Xu
1University of Massachusetts Medical Center, Division of Thoracic Surgery, 271 Carew Street, Springfield, Massachusetts 01104, USA.
Abstract:
Cutaneous metastases from esophageal adenocarcinoma are exceedingly rare. With the institution of multimodality treatments and surgical resection for esophageal adenocarcinoma, loco-regional disease recurrence has been dramatically reduced. In this report, we present a 59-year-old white male with adenocarcinoma of the distal esophagus that was treated with neoadjuvant chemotherapy and radiation therapy, followed by surgical excision. After a disease free interval of two years the patient presented with cutaneous metastatic disease.
