Related Experiment Video

Updated: Jul 18, 2026

Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture
04:02

Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture

Published on: November 25, 2025

[Symptomatic gallstone disease: an indication for surgery]

A H W Schiphorst1, M G H Besselink, N G Venneman

  • 1St. Antonius Ziekenhuis, Postbus 2500, 3430 EM Nieuwegein.

Nederlands Tijdschrift Voor Geneeskunde
|November 30, 2006
PubMed

Insights

Recognizing

Area of Science:

  • Gastroenterology
  • Hepatobiliary Medicine

Background:

  • Gallstones affect 10-5% of Dutch adults, with only 10% experiencing symptoms.
  • Asymptomatic gallstone carriers face a 1-2% annual risk of complicated gallstone disease.

Observation:

  • Three male patients (56-66 years) with ultrasonographically proven gallstones experienced 'warning colics' but did not undergo cholecystectomy.
  • One patient died from sepsis due to infected pancreatic necrosis.
  • The other two patients recovered fully after laparoscopic cholecystectomy.

Findings:

  • 58% of patients admitted with complicated gallstone disease reported prior 'warning colics'.
  • Timely cholecystectomy after recognizing warning colics can prevent severe complications.

Implications:

  • Prompt surgical intervention (cholecystectomy) is crucial for patients with intermittent upper-abdominal pain and confirmed gallstones.
  • Early recognition and treatment of warning colics can avert life-threatening complications such as infected pancreatic necrosis.

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