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Updated: Jul 18, 2026

Isolation of Umbilical Cord-Derived Mesenchymal Stem Cells with High Yields and Low Damage
Published on: July 5, 2024
[Freezing umbilical-cord blood and bone marrow for one's own use: present-day quackery?]
D D M Braat1, C L Mummery, A V M B Schattenberg
1Universitair Medisch Centrum St Radboud, Postbus 9101, 6500 HB Nijmegen. d.braat@obgyn.umcn.nl
Abstract:
In the Netherlands, the practice of private freezing and banking of umbilical-cord blood is increasing. In a questionnaire, Dutch midwives and gynaecologists were asked about their attitude towards cord-blood collection if asked to perform this after delivery. The response rate was 35% (125/356) and 71% (71/100), respectively. Two-thirds of those asked responded that they would comply. The most common application of cord blood is in the treatment of (malignant) blood disorders. The use of autologous cord blood is, however, often not the best choice for treating leukaemia in young children and the number of stem cells is often too low in a single-cord blood sample to treat older children and adults. Although frequently suggested in the lay press, there is no proven effect in other indications, such as amyotrophic lateral sclerosis, multiple sclerosis and myocardial infarction. Information on therapeutic applications of cord blood from companies with commercial interests is leading to the exploitation ofpregnantwomen. The government should consider limiting this practice and prohibiting the activities of these companies in the Netherlands pending scientific evidence for their claims.
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