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Updated: Jul 18, 2026
Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
Published on: August 14, 2019
The effectiveness of a treatment protocol for male lower urinary tract symptoms in general practice: a practical
Roelf J C Norg1, Kees van de Beek, Piet J M Portegijs
1Department of General Practice, Care and Public Health Research Institute, Maastricht University, Netherlands. roelf.noerg@hag.unimaas.nl
Background:
Randomised controlled trials have shown the efficacy of several treatment modalities for lower urinary tract symptoms (LUTS) in selected populations. The effectiveness in daily practice has hardly been investigated, especially in primary care and is dependent on choices between all possible treatment options and best investigated in a comprehensive study, including all treatment modalities (watchful waiting, alpha-blockers, 5-alpha-reductase inhibitors, and surgery).
Aim:
Assessment of the effectiveness of a comprehensive treatment protocol for LUTS in primary care.
Design Of Study:
Randomised controlled trial.
Setting:
Fourteen general practices in the Netherlands.
Intervention:
treatment protocol based on a formalised expert opinion. Control condition: usual care.
Study Population:
208 subjects with moderate to severe LUTS (IPSS > or =8, median = 13).
Outcome Measures:
symptom severity (IPSS [International Prostate Symptom Score]), bother score (Dan-PSS [Danish Prostate Symptom Score]), and maximum urinary flow (Q(max)); incidence of acute urinary retention and urinary tract infections.
Results:
In the intervention group markedly more subjects used an alpha-blocker at end of follow-up than in the usual care group (24% versus 6%). No significant differences were found between intervention and control group in IPSS, Q(max) or Dan-PSS.
Conclusion:
alpha-blockers and watchful waiting are the most frequent treatment modalities for LUTS in primary care. Our study showed no evidence that a protocol using well-defined indications for all possible treatment modalities based on a formalised expert opinion procedure has added value. Based on our results, we cannot recommend a broadening of the indication for alpha-blockers, which, however, seems to be the current trend.
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